Stay up to date on all things depression. Sign up and we’ll send you the latest news, resources, scientific breakthroughs, events, tips, and much more.

Share this post on your profile with a comment of your own:

Successfully Shared!

View on my Profile

Brain Connectivity in Depression

October 28, 2019


Beth Israel Deaconess Medical Center is recruiting for a clinical trial that studies how stimulation to a certain part of the brain may benefit people with depression. The study uses transcranial magnetic stimulation (TMS) and targets those who have previously been resistant to treatment (medical-refractory).


Study Information

 To ensure good health, only patients from two sites are invited to participate:

  • The Clinical Program of FDA approved TMS at the Berenson-Allen Center
  • The Butler TMS Clinic

The study includes:

  •  Hour-long MRI scanning session
  • Optional DNA-sample
  • Up to three 20-minute to mark the site of TMS stimulation
  • Questionnaires
  • A behavioral testing battery before and after TMS treatment


Inclusion Criteria

  • Male or female
  • Ages 18 to 70 years old
  • Have previously received or will receive TMS to the left dorsal-lateral prefrontal cortex


Exclusion Criteria

  • Any current or past history of a major psychiatric illness other than depression
  • Any significant current neurological illness (e.g. a history of seizures or unexplained loss of consciousness, a family history of epilepsy, signs of increased intracranial pressure, previously abnormal MRI scans, parkinsonism or dementia)
  • Patients who are pregnant or lactating (by menstrual history)
  • Use illegal substances
  • Positive MRI screen that would prevent patient from undergoing magnetic resonance imaging
  • Subjects that cannot adhere to the study requirements



You may participate in this study at Butler Hospital in Rhode Island, United States, 02906. If you have any questions or concerns feel free to contact Linda Carpenter, MD at 401-455-6632 or at



This clinical trial is sponsored by Beth Israel Deaconess Medical Center. The Principal Investigator is Linda Carpenter, MD and the Sub-Investigators are Eric Tirrell, BS and Gina Sensale, BS.

Clinical Trials

View All Clinical Trials

Mindful Breathing and tDCS for Depression

The Clinical and Translational Science Institute of the University of…

Sleep and Healthy Aging Research for Depression

The University of California, Los Angeles, is conducting a clinical trial that examines the effect of inflammatory…

Set Your Goal: Engaging Go/No-Go Active Learning

Depression and anxiety are the largest contributors to disease and disability, affecting around 300 million people. This research study aims to…

A Family Depression Prevention Program

Depression is a major public health problem affecting over 15 million U.S. adults annually and is especially prevalent in those of parenting age.…

Send this to a friend